• Object ID: 00000018WIA30748970GYZ
  • Topic ID: id_40024820 Version: 1.4
  • Date: Mar 28, 2022 2:08:30 PM

Dynamic Susceptibility Contrast scan protocol

Consider these tradeoffs as you change scan parameters for images that are post-processed with these READY View applications: BrainStat, BrainStat AIF, and MR Standard. The tables below apply to the following MR field strengths:

  • 1.5T
Table 1. 2D Single-Shot Gradient-Echo, Echo-Planar Imaging
Scan parameterValueConsiderations
TR1000- 1500 msTR affects T2* weighting, which is required to reduce T1 effect from leakage contamination.
TE30-60 msDecrease the TE value for 3.0T protocols to 30-40 ms.
Flip angle60 degreesThe value does not change for field strength.
Bandwidth250 kHzSelect Ramp Sampling User CV.
FOV24 - 28 cmThe value does not change for field strength.
Slice thickness4 - 7 mmAs the slice thickness decreases:
  • The magnetic susceptibility decreases.
  • SNR decreases. Consider decreasing the matrix size to increase SNR.
Slice spacing0-1 mmThe value does not change for field strength.
Matrix7 mm slice = 128 x 128

4 mm slice = 64 x 64

As the matrix size increases, increase slice thickness to compensate for the SNR loss.
NEX1The value does not change for field strength.
Frequency directionRight/LevelSwap phase and frequency to reduce Nyquist ghost artifact.
Imaging OptionsMulti-phase, ASSETBrainstat GVF requires a larger amount of time-points compared to Brainstat AIF.
Temporal resolutiondetermined by the TRThe shorter the TR the better. Brainstat requires high temporal resolution data (typically TR< or = 1500 ms).
Acquisition timeAIF is approximately 60 seconds

GVF is 40% longer than AIF

Assumes a temporal resolution of 1.5 seconds.
Number of slicesChanges as TR changesBe aware of the effect of the number of prescribed slices has on the TR value. The minimum TR can double when the number of slices is increased.
Table 2. 2D Single-Shot Spin-Echo Echo-Planar Imaging
Scan parameterValueConsiderations
TR1000- 1500 msTR affects T2* weighting, which is required to reduce T1 effect from leakage contamination.
TE50-80 msDecrease the TE value for 3.0T protocols to 30-40 ms.
Flip angle90 degreesThe value does not change for field strength.
Bandwidth250 kHzSelect Ramp Sampling User CV.
FOV24 - 28 cmThe value does not change for field strength.
Slice thickness4 - 7 mmAs the slice thickness decreases:
  • The magnetic susceptibility decreases.
  • SNR decreases. Consider decreasing the matrix size to increase SNR.
Slice spacing0-1 mmThe value does not change for field strength.
Matrix7 mm slice = 128 x 128

4 mm slice = 64 x 64

As the matrix size increases, increase slice thickness to compensate for the SNR loss.
NEX1The value does not change for field strength.
Frequency directionRight/LevelSwap phase and frequency to reduce Nyquist ghost artifact.
Imaging OptionsMulti-phase, ASSETBrainstat GVF requires a larger amount of time-points compared to Brainstat AIF.
Temporal resolutiondetermined by the TRThe shorter the TR the better. Brainstat requires high temporal resolution data (typically TR< or = 1500 ms).
Acquisition timeAIF is approximately 60 seconds

GVF is 40% longer than AIF

Assumes a temporal resolution of 1.5 seconds.
Number of slicesChanges as TR changesBe aware of the effect of the number of prescribed slices has on the TR value. The minimum TR can double when the number of slices is increased.